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International Journal of Nephrology
Volume 2012, Article ID 231018, 5 pages
http://dx.doi.org/10.1155/2012/231018
Research Article

Comparison of Mortality between Japanese Peritoneal Dialysis and Hemodialysis Patients: A 5-Year Multicenter Follow-Up Study

1Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, 2-2-2, Iida-Nishi, Yamagata, Yamagata 990-9585, Japan
2Department of Internal Medicine, Okitama Public General Hospital, Kawanishi 992-0601, Japan
3Department of Internal Medicine, Nihonkai General Hospital, Sakata 998-8501, Japan
4Dialysis Center, Yabuki Hospital, Yamagata 990-0043, Japan
5Dialysis Center, Keijinkai Hospital, Osaki 989-6117, Japan
6Department of Internal Medicine, Yamagata City Hospital Saiseikan, Yamagata 990-0042, Japan

Received 2 February 2012; Accepted 5 April 2012

Academic Editor: Jaime Uribarri

Copyright © 2012 Kazuko Suzuki et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

To examine the relationship between dialysis modality and prognosis in Japanese patients, we conducted a prospective multicenter observational study. We recruited 83 background-matched peritoneal dialysis (PD) and 83 hemodialysis (HD) patients (average age, 64.9 years; men, 53.6%; diabetic patients, 22.9%; median duration of dialysis, 48 months in all patients) and followed them for 5 years. During the follow-up period, 27 PD patients (16 cardiovascular and 11 non-cardiovascular deaths) and 27 HD patients died (14 cardiovascular and 13 non-cardiovascular deaths). There were 8 PD patients switched to HD, and 6 PD patients received renal transplantation. Kaplan-Meier analysis revealed that the crude survival rate was not significantly different at the end of 5 years (PD 67.5% versus 67.5%, log-rank ). The difference in cardiovascular and non-cardiovascular mortalities between PD and HD was not statistically significant. Multivariate Cox analysis showed that the independent predictors for death were age and serum albumin levels, but not the dialysis modality. This study showed that the overall mortality was not significantly different between PD and HD patients, which suggests that dialysis modality might not be an independent factor for survival in Japanese patients.