Research Article

Vitamin E, Vitamin C, or Losartan Is Not Nephroprotectant against Cisplatin-Induced Nephrotoxicity in Presence of Estrogen in Ovariectomized Rat Model

Table 1

Summary of the treatment in the groups. Estradiol was injected at the beginning of each week. CP was administrated as a single dose at the beginning of the second week. The vitamins and losartan were injected daily during the second week.

GroupFirst weekSecond week

1EstradiolEstradiol + CP + saline
2EstradiolEstradiol + CP + vitamin E
3EstradiolEstradiol + CP + vitamin C
4EstradiolEstradiol + CP + losartan
5SalineCP
6EstradiolEstradiol
7SalineSaline