Table 1: Patients’ characteristics and clinical course in subjects with end-stage renal failure presenting with calciphylaxis.

SubjectPatient 1Patient 2Patient 3Patient 4Patient 5Patient 6

Age (years)485363727486
Cause of ESRFDiabetesChronic GNDiabetesDiabetesDiabetesObstructive uropathy
Duration RRT (months)123624211512
Site of lesionExtensive*DistalDistalExtensiveDistalDistal
MicroorganismPseudomonasMRSAKlebsiellaPseudomonasPseudomonasMRS seudomonas
Mode of therapy**Cinacalcet STSPTHX HBOPTHX HBO STS prednisoloneCinacalcet prednisoloneSTS HBO amputationCinacalcet HBO
Cause of deathSepsisMyocardial infarctionSepsisMyocardial infarctionSepsisNot applicable
ComorbiditiesDM ESRF IHD HTN AsthmaEpilepsy ESRF goutDM ESRF goutIHD DM ESRF MGUSDM ESRF HTN arthritisESRF
Skin lesion outcomeFailedHealedFailedHealedFailedHealed
Survival (months)132544Alive

ESRF: end-stage renal failure, GN: glomerulonephritis, RRT: renal replacement therapy, *: extensive skin lesions involving the lower limbs, genitalia, abdominal wall, and breast, MRSA: methicillin resistant Staph aureus, **: mode of therapy apart from general wound care and antibiotics, STS: sodium thiosulphate, PTHX: parathyroidectomy, HBO: hyperbaric oxygen, IHD: ischemic heart disease, HTN: hypertension, MGUS: monoclonal gammopathy of unknown significance.