International Journal of Nephrology / 2012 / Article / Fig 1

Review Article

Inflammatory Mechanisms of Organ Crosstalk during Ischemic Acute Kidney Injury

Figure 1

AKI and organ crosstalk. AKI induces remote organ injury in the heart, brain, lungs, liver, and gut involving multiple inflammatory pathways, including increased expression of soluble proinflammatory mediators, innate and adaptive immunity, cellular apoptosis, physiologic derangements and genomic changes.
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