Review Article

Understanding Nephrogenic Systemic Fibrosis

Table 1

Permissive factors presumably contributing to the development of NSF lesions.

Associated proinflammatory conditionsAssociated biochemical milieu

Vascular injury/vascular surgery proceduresAcidosis
Thrombotic events/procoagulant statesIron
Severe infectionErythropoietin
Chronic hepatitis C, hepatic disease and
liver transplantation
Calcium and phosphate
Hyperparathyroidismā€‰
Hypothyroidismā€‰