Degree of Acute Kidney Injury before Dialysis Initiation and Hospital Mortality in Critically Ill Patients
Table 2
Distribution of ICU admission diagnoses in patients with AKI requiring dialysis, by severity of kidney injury groups.
Admission diagnosis category
Group I
Group II
Group III
Group IV
P value
(N = 2,744; 100%)
N = 1,006%
N = 574%
N = 856%
N = 308%
Cardiovascular disorders (N, 478; 17.4%)
21
19.9
12.6
14.6
<0.0001
Gastrointestinal disorders (N, 206; 7.5%)
9.7
8.2
5.0
5.8
0.0009
Abdominal surgery (N, 109; 4%)
2.5
3.8
6.5
1.9
<0.0001
Hematological disorders (N, 42; 1.5%)
1.6
1.7
1.4
1.3
0.94
Electrolyte abnormalities (N, 150; 5.5%)
4.9
3.5
1.9
21.1
<0.0001
Malignancies (N, 135; 4.9%)
2.2
5.2
9.0
1.9
<0.0001
Neurological disorders (N, 63; 2.3%)
2.9
1.2
2.1
2.9
0.158
Orthopedic surgery (N, 56; 2.0%)
2.4
1.0
1.5
1.3
0.192
Kidney disorders (N, 278; 10.1%)
12.3
8.0
4.1
23.7
<0.0001
Respiratory disorders (N, 353; 12.9%)
11.8
14.5
14.5
8.8
0.031
Infections/sepsis (N, 422; 15.4%)
19.5
14.8
12.1
12.0
<0.0001
Cardiothoracic surgery (N, 383; 14%)
6.1
15.8
26.3
1.9
<0.0001
Liver failure (N, 69; 2.5%)
3.5
2.8
1.6
1.3
0.034
Group (Grp) I: 0.3 mg/dL to <2 time increase; II: ≥2 to <3 times increase; III: >3 times increase; IV: <0.3 mg/dL increase in creatinine before dialysis initiation; admission diagnosis categories are mutually exclusive and add up to 100%; trauma and gynecological diagnoses were not included due to 1 and 0 patients in these categories, respectively; data expresses row frequencies.
