Cystatin C as a Predictor of Mortality and Cardiovascular Events in a Population with Chronic Kidney Disease
Table 2
Incidence of cardiovascular events and overall mortality by cystatin C and serum creatinine, categorized by tertiles.
Cystatin C
Creatinine
Tertile 1
Tertile 2
Tertile 3
Tertile 1
Tertile 2
Tertile 3
Participants number
59
60
61
59
56
65
Persons/year
166
196
163
198
151
177
Total cardiovascular events
Participants number
13
17
23
16
15
22
Incidence/1000 persons-year
78
87
141
81
99
124
HR
0.782 (0.363–1.688)
0.743 (0.381–1.449)
—
0.802 (0.401–1.602)
0.715 (0.345–1.478)
—
Fatal cardiovascular events
Participants number
0
2
10
1
4
7
Incidence/1000 persons-year
0
10
61
5
26
39
HR
0
0.198 (0.040–0.987)
—
0.126 (0.013–1.265)
0.403 (0.093–1.740)
—
Non-fatal cardiovascular events
Participants number
13
15
13
15
11
15
Incidence/1000 persons-year
78
77
80
76
73
85
Total mortality
Persons-year
166
199
176
198
151
192
Participants number
1
2
18
2
5
14
Incidence/1000 persons-year
6
10
102
10
33
73
HR
0.060 (0.008–0.447)
0.094 (0.022–0.406)
—
0.178 (0.039–0.805)
0.329 (0.115–0.442)
—
Renal events
Persons-year
166
197
166
198
151
177
Participants number
0
5
6
0
2
9
Incidence/1000 persons-year
0
25
36
0
13
51
HR
0
0.463 (0.095–2.254)
—
0
0.142 (0.035–0.577)
—
Event risks were evaluated in Cox proportional model, adjusted for age, gender, BMI, previous cardiovascular event, and tobacco consumption. Values in bold letters means that ; HR: hazard risk.
