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International Journal of Nephrology
Volume 2014, Article ID 284172, 8 pages
Research Article

Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac Pacemakers

1CASMU Arrhythmia Service, 8 de Octubre 3310, 11600 Montevideo, Uruguay
2British Hospital, Avenida Italia 2420, 11600 Montevideo, Uruguay
3Uruguayan Registry of Dialysis, Uruguay
4Nephrology Clinic, Hospital de Clinicas, Faculty of Medicine, The University of the Republic, Avenida Italia s/n, 11600 Montevideo, Uruguay

Received 28 January 2014; Revised 6 April 2014; Accepted 7 April 2014; Published 26 May 2014

Academic Editor: David B. Kershaw

Copyright © 2014 Gabriel Vanerio et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


End stage renal disease is a relatively frequent disease with high mortality due to cardiac causes. Permanent pacemaker (PM) implantation rates are also very common; thus combination of both conditions is not unusual. We hypothesized that patients with chronic kidney disease with a PM would have significantly higher mortality rates compared with end stage renal disease patients without PM. Our objectives were to analyze mortality of patients on renal replacement therapy with PM. 2778 patients were on renal replacement therapy (RRT) and 110 had a PM implanted during the study period. To reduce the confounding effects of covariates, a propensity-matched score was performed. 52 PM patients and 208 non-PM matched patients were compared. 41% of the PM were implanted before entering the RRT program and 59% while on RRT. Mortality was higher in the PM group. Cardiovascular disease and infections were the most frequent causes of death. Propensity analysis showed no differences in long-term mortality between groups. We concluded that in patients on RRT and PM mortality rates are higher. Survival curves did not differ from a RRT propensity-matched group. We concluded that the presence of a PM is not an independent mortality risk factor in RRT patients.