Research Article

Incidence, Severity, and Outcomes of Acute Kidney Injury in Octogenarians following Heart Valve Replacement Surgery

Table 3

Preoperative characteristics and hospital course in AKI and non-AKI octogenarians.

Preoperative characteristicsNo AKI, mean ± SD, 
AKI, mean ± SD, 
value

Age, median [range]84.1 ± 2.8 [80.1–93.4]83.9 ± 2.8 [80.1–92.0]0.49
Sex, male (%)57 (51.3)58 (59.2)0.26
BMI, kg/m227.1 ± 4.928.4 ± 5.70.09
HTN (%)72 (64.9)55 (56.1)0.20
Diabetes (%)18 (16.2)22 (22.4)0.25
Hyperlipidemia on lipid-lowering agents (%)62 (55.9)42 (42.9)0.06
Chronic pulmonary disease (%)19 (17.1)14 (14.3)0.58
Preexisting CKD (%)8 (7.2)26 (26.5)<0.0001
Prior myocardial infarction (%)12 (10.8)23 (23.5)0.01
CAD (%)78 (70.3)65 (66.3)0.54
Peripheral vascular, cerebrovascular, or carotid artery disease (%)29 (26.1)36 (36.7)0.10
CHF (%)94 (84.7)73 (74.5)0.07
Charlson Comorbidity Index2.392.910.03
Pre-op EF, %53.7 ± 15.555.7 ± 14.30.34
Pre-op hemoglobin, g/dL12.8 ± 1.611.9 ± 1.60.03

Hospital course

Surgical duration, min331.0 ± 82.8369.1 ± 108.50.005
CABG, yes or no (%)64 (57.7)58 (59.2)0.82
IABP (%)2 (1.80)9 (9.18)0.02
Cross clamp time, min69.7 ± 30.169.0 ± 32.30.85
CPB, min96.7 ± 39.3101.3 ± 43.30.42
Net intraoperative fluid balance, L6.87 ± 2.578.12 ± 4.280.01
Total intraoperative saline, L0.90 ± 0.721.16 ± 0.950.02
Intraoperative hemoglobin, g/dLa8.28 ± 1.047.92 ± 1.040.01
RBC on operative day, L0.74 ± 0.631.06 ± 1.030.008
RBC during hospitalization, L0.92 ± 0.861.54 ± 1.650.0007
Length of hospital stay, day9.2 ± 4.2 ()14.0 ± 11.7 ()<0.0001
Discharge creatinine, mg/dL1.09 ± 0.251.46 ± 0.56<0.0001

aThe lowest hemoglobin during the operation.