The Effects of Simvastatin on Proteinuria and Renal Function in Patients with Chronic Kidney Disease
Table 2
Changes of metabolic profiles after 53 weeks of statin treatment.
Variables
Mean changes
value
Simvastatin
Nonsimvastatin
SBP (mmHg)
−5.72 ± 21.88
−0.77 ± 20.19
0.405
DBP (mmHg)
−1.84 ± 13.89
−4.50 ± 13.64
0.493
Cholesterol (mg/dL)
−52.44 ± 106.05
−6.65 ± 36.88
0.045
Triglyceride (mg/dL)
−34.68 ± 140.77
−15.81 ± 83.44
0.561
HDL (mg/dL)
0.36 ± 15.95
1.65 ± 20.31
0.802
LDL (mg/dL)
−41.28 ± 79.96
−3.81 ± 25.44
0.033
Non-HDL (mg/dL)
−56.04 ± 111.34
−8.50 ± 29.78
0.049
AST (U/L)
−2.12 ± 7.57
5.15 ± 18.83
0.079
ALT (U/L)
3.36 ± 28.03
10.96 ± 44.41
0.470
Data are expressed as mean changes of 53 weeks ± SD; ALT: alanine aminotransferase; AST: aspartate aminotransferase; DBP: diastolic blood pressure; HDL: high density lipoprotein; LDL: low density lipoprotein; SBP: systolic blood pressure.
