Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis
Table 4
Univariate and multivariate regression analyses demonstrating clinical factors showing correlation with renal pathological activity index (AI).
Univariate regression
Multivariate regression = 0.386
Beta
SE.
value
Beta
SE.
value
Age (yrs)
−0.09
0.02
<0.001
−0.10
0.02
<0.001
SBP (mmHg)
0.05
0.01
<0.001
DBP (mmHg)
0.08
0.02
<0.001
0.05
0.02
0.001
Serositis
1.97
0.68
0.004
Anti-dsDNA
2.23
0.69
0.001
1.18
0.57
0.039
Blood urea nitrogen (mg/dL)
0.08
0.01
<0.001
Serum creatinine (mg/dL)
1.43
0.27
<0.001
−0.98
0.43
0.024
Estimated GFR (mL/min/1.73 m2)
−0.04
0.01
<0.001
−0.05
0.01
<0.001
Hemoglobin (g/dL)
−0.81
0.12
<0.001
−0.40
0.12
0.001
Serum albumin (g/dL)
−1.21
0.40
0.003
UPCR (g/g creatinine)
0.21
0.09
0.016
0.18
0.07
0.014
Microscopic hematuria
2.50
0.56
<0.001
1.44
0.48
0.003
Independent variables in the multivariate model were chosen using a stepwise regression analysis where all significant variables listed in the univariate analysis were included. DBP: diastolic blood pressure, GFR: glomerular filtration rate, SBP: systolic blood pressure, and UPCR: urine protein creatinine ratio.
