Proteasome Activators, PA28α and PA28β, Govern Development of Microvascular Injury in Diabetic Nephropathy and Retinopathy
Deletion of the PA28α and PA28β genes suppresses the glomerular expression of OPN and MCP-1 in STZ-injected mice. (a) qPCR analysis of OPN and (b) MCP-1 mRNA in wild type and Pa28αβDKO glomeruli without or with four months of STZ injection. per group. Results presented as mean ± SEM. .
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