Research Article
Analysis of T Cell Subsets in Adult Primary/Idiopathic Minimal Change Disease: A Pilot Study
Figure 2
(a) Percentage of cortex infiltration of CD8+ T cells, CD4+ T cells, and CD19+ B cells in kidney tissue of 9 patients with primary MCD. (b) Cell densities of the infiltrating Foxp3+ Treg cells, IL-17+ Th17 cells, and granzyme B+ cytotoxic cells in kidney tissue of these primary MCD patients. (c) Ratios of the cell densities of Th17 cells over Foxp3+ Treg cells and cytotoxic cells over Treg cells, infiltrating kidney tissue of primary MCD patients (the horizontal black line indicates the arbitrary ratio reference value of 1; the red arrows indicate the direction of the ratios, increased or decreased). Cells were detected by immunohistochemistry, and the median percentages, cell densities, and their ratios are reported.
(a) |
(b) |
(c) |