Renal Function and Death in Older Women: Which eGFR Formula Should We Use?
Table 2
Clinical characteristics of SOF participants by CKD- eGFR category.
Baseline characteristics
Overall ()
CKD- eGFR category (mL/min/1.73 m2)
value
≥75
60 to 74
45–59
<45
()
()
()
()
Age, years, mean (SD)
79.5 (4.6)
77.7 (4.1)
79.4 (4.2)
81.3 (4.8)
82.0 (4.8)
<0.001
Race/ethnicity, (%)
<0.001
White
1159 (89.9)
355 (82.2)
399 (92.8)
270 (95.1)
135 (94.4)
Black
130 (10.1)
77 (17.8)
31 (7.2)
14 (4.9)
8 (5.6)
Education, (%)
0.031
Less than high school
229 (17.8)
62 (14.4)
69 (16.1)
65 (23.0)
33 (23.1)
High school
538 (41.8)
190 (44.1)
182 (42.4)
116 (41.0)
50 (35.0)
College/grad school
519 (40.4)
179 (41.5)
178 (41.5)
102 (36.0)
60 (42.0)
Body mass index, kg/m2, mean (SD)
26.8 (5.0)
26.1 (4.9)
27.1 (5.0)
27.0 (4.8)
27.4 (5.2)
0.008
Current smoker, (%)
58 (4.5)
27 (6.3)
15 (3.5)
12 (4.2)
4 (2.8)
0.167
Self-rated health good/excellent, (%)
1035 (80.4)
366 (84.7)
357 (83.0)
217 (76.4)
95 (66.9)
<0.001
Hypertension, (%)
795 (61.7)
235 (54.4)
242 (56.3)
196 (69.0)
122 (85.3)
<0.001
Diabetes mellitus, (%)
95 (7.4)
33 (7.6)
23 (5.4)
23 (8.1)
16 (11.3)
0.112
Self-reported stroke, (%)
60 (4.7)
18 (4.2)
10 (2.3)
20 (7.0)
12 (8.5)
0.003
Self-reported coronary heart disease, (%)
246 (19.1)
73 (16.9)
67 (15.6)
62 (21.8)
44 (31.0)
<0.001
Self-reported congestive heart failure, (%)
65 (5.1)
21 (4.9)
12 (2.8)
20 (7.0)
12 (8.5)
0.016
CKD- eGFR, mean (SD)
66.7 (16.7)
84.6 (7.1)
67.6 (4.2)
53.5 (4.1)
36.3 (7.2)
<0.001
Follow-up time, years, mean (SD)
9.2 (4.0)
10.2 (3.8)
9.6 (3.9)
8.3 (4.0)
6.8 (4.1)
<0.001
eGFR, estimated glomerular filtration rate; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; cr, creatinine; cysc, cystatin C. As determined by self-report or any disease-specific medication use. Coronary heart disease includes myocardial infarction, angina, and other heart diseases.
