Research Article

Acid-Base Status Disturbances in Patients on Chronic Hemodialysis at High Altitudes

Table 1

Patient characteristics.

VariableNumber of patients
n(), median (IQR) or mean (±SD†)n=93

Age (years)60,9 (50,8 – 71,1)

Male gender64 (68,8)

Time on dialysis (months)48,5 (34,6 – 88,4)

Dry weight (Kg)63 (54 – 73)

Interdialytic weight gain (Kg)1,5 (1 – 2,3)

Etiology of CKD
 Diabetes mellitus36 (38,7)
 Hypertension31 (33,3)
 Primary glomerulopathy and autoimmune disease10 (10,7)
 Obstructive3 (3,23)
 Polycystic kidney disease6 (6,46)
 Other causes7(7,53)

Dialysis related parameters
 Pre-dialysis systolic blood pressure (mmHg)132 (± 21,3)
 Pre-dialysis diastolic blood pressure (mmHg)74,8 (± 16,6)
 Post-dialysis systolic blood pressure (mmHg)133 (± 20,2)
 Post-dialysis diastolic blood pressure (mmHg)73 (± 12,3)
 Therapy time (minutes)244 (± 14,1)
 Dialyzer
  Revaclear 30042 (45,2)
  Revaclear 40046 (49,5)
  Polyflux 140H5 (5,38)
 Type of extracorporeal system anticoagulation
  Unfractionated heparin86 (92,5)
  Low molecular weight heparin4 (4,3)
  No anticoagulation3 (3,23)
 Single pool Kt/V1.57 (1.43 – 1,8)
 nPCR1,04 (± 0.2)
 Malnutrition-Inflammation Score (MIS)5 (4 – 7)
 Protein intake (grams/day)68 (58 – 75)
 Lipid intake (grams/day)42,6 (± 12,5)
 Carbohydrate intake (grams/day)197 (± 44,2)

Laboratory parameters
 Serum albumin (gr/dL)4,21(± 0,31)
 PTHi ‡ (ng/mL)388 (242 – 573)
 Calcium (mg/dL)8,75 (±0,62)
 Phosphate (mg/dL)4,63 (±1,19)
 Potassium (mEq/L)5 (± 0,63)
 Hemoglobin (g/dL)12,3 (± 1,64)

Phosphate binding therapy
 Calcium carbonate66 (71)
 Aluminum Hydroxide43 (46,2)
 Sevelamer Chlorhydrate4 (4,3)

Interquartile Range (IQR).
†Standard deviation.
‡Intact parathyroid hormone (PTHi).