Clinical Study

Mortality and Recovery of Renal Function in Acute Kidney Injury Patients Treated with Prolonged Intermittent Hemodialysis Sessions Lasting 10 versus 6 Hours: Results of a Randomized Clinical Trial

Table 1

Clinical and laboratory characteristics of patients with AKI treated with PHD.

ParametersGeneral (n = 194)G1 (n = 104)G2 (n = 90)p value

Age (in years)60.8 ± 14.961.4 ± 14.460.2 ± 15.50.55
Males, n (%)135 (69.5)73 (70.1)62 (68.8)0.84
Weight74.8 ± 22.574.1 ± 2475.6 ± 20.80.63
Infectious focus n (%)
Pulmonary80 (41.2)43 (41.3)37 (41.2)0.97
Abdominal69 (35.5)31 (29.8)38 (42.2)0.07
Comorbidities, n (%)
 (i) SAH102 (52.5)58 (55.7)44 (48.8)0.33
 (ii) DM53 (27.2)29 (27.8)24 (26.6)0.84
 (iii) CKD19 (9.7)12 (11.5)7 (7.7)0.37
ATN-ISS0.77 ± 0.10.76 ± 0.10.77 ± 0.20.87
SOFA14.2 ± 2.914.1 ± 314,4 ± 2,90.47
Pre-dialysis FB (l)3.36 ± 1.83.27 ± 1.93.47 ± 1.70.47
Ur (mg/dl)155.3 ± 105.7158.6 ± 59.5151.6 ± 141.20.64
Cr (mg/dl)3.7 ± 1.53.7 ± 1.43.6 ± 1.70.64
K (mEq/L)4.7 ± 14.7 ± 14.8 ± 10.48
Bic (mEq/L)19.1 ± 4.618.8 ± 4.719.5 ± 4.60.39
Mechanical Ventilation182 (93.8)98 (94.2)84 (93.3)0.96
Initial vasoactive drug dose0.55 ± 0.180.55 ± 0.170.56 ± 0.190.97
Final vasoactive drug dose0.69 ± 0.190.69 ± 0.160.70 ± 0.200.91

Values are presented in frequency, mean values and standard deviation, median, and proportions.
AKI: acute renal injury, PHD: prolonged hemodialysis, SAH: systemic arterial hypertension, DM: diabetes mellitus, CKD: chronic kidney disease, ATN-ISS: acute tubular necrosis individual severity score, SOFA: sequential organ failure assessment score, FB: fluid balance, Ur: urea, Cr: creatinine, K: potassium, Bic: bicarbonate, and UF: ultrafiltration.