Vascular Calcification in Chronic Kidney Disease: The Role of Inflammation

Figure 1

(a-f) Representative vascular findings in nonrenal control patients (a, c, e) and patients with chronic kidney disease (CKD). (a, b) Marked thickening of coronary arteries in CKD patients (b) compared to nonrenal controls (a). HE-stain. (c, d) Marked calcification of the arterial intima and media and atherosclerotic coronary plaques in CKD patients (d) compared to nonrenal controls (d). Von Kossa stain. (e, f) Increased number of CD68 positive macrophages in the vascular wall of CKD patients (f) compared to nonrenal controls (e). Immunohistochemistry.

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