Drug-Related Problems and Associated Factors among Patients Admitted with Chronic Kidney Disease at Jimma University Medical Center, Jimma Zone, Jimma, Southwest Ethiopia: A Hospital-Based Prospective Observational Study
Table 3
Prevalence of MRPs and their causes among CKD patients at JUMC, Jimma Zone, Jimma, Southwest Ethiopia, from April 1 to September 30, 2018.
MRPs domain
DRP subdomain
Cause
Frequency
Indication
Need additional drug therapy
A medical condition requires the initiation of drug therapy
52 (26)
62 (31)
Preventive drug therapy is required to reduce the risk of developing a new condition
10 (5)
Unnecessary drug therapy
There is no valid medical indication for the drug therapy at this time
5 (2.5)
9 (4.5)
Multiple drug products are being used for condition that requires single-drug therapy
4 (2)
Effectiveness
Ineffective
The drug is not the most effective for the medical problem
12 (6)
20 (10)
The medical condition is refractory to the drug product
8 (4)
Dose too low
The dose is too low to produce the desired response
32 (16)
36 (18)
The dosage interval is too infrequent to produce the desired response
4 (2)
Safety
Adverse drug reaction
The drug product causes an undesirable reaction that is not dose-related
3 (1.5)
4 (2)
A drug interaction causes an undesirable reaction that is not dose-related
1 (0.5)
Dose too high
Dose is too high
19 (9.5)
29 (14.5)
The dosing frequency is too short
10 (5)
Compliance
Noncompliance
The patient/caregiver does not understand the instructions
5 (2.5)
40 (20)
The patient/caregiver prefers not to take/give the medication
12 (6)
The patient/caregiver forgets to take/give the medication
