Research Article

The Role of Cathepsin B in Peritoneal Fibrosis due to Peritoneal Dialysis

Table 1

Characteristics of the patients.

VariablesDataa

Age (years)59 ± 13
Sex, male/female (% of male)35/33 (51%)
Diabetes mellitus, yes/no (%)61/7 (90%)
PD vintageb (days)365 (124–983)
Urine volumec (ml/day)877 ± 662
Renal Kt/Vureac0.8 ± 0.8
Peritoneal Kt/Vurea1.2 ± 0.5
Total Kt/Vurea2.0 ± 0.8
D/Pcr0.72 ± 0.12
Serum procathepsin B (μg/L)3.6 ± 1.6
Effluent procathepsin B (μg/L)5.4 (3.9–8.9)
Serum cystatin C (mg/L)4.4 ± 1.3
Effluent cystatin C (mg/L)0.6 (0.4–0.8)
Effluent CA 125 (IU/L)41.3 (23.3–62.9)

aData are expressed as mean ± SD, median (IQR), or %. bInterval from PD catheter insertion to the day of obtaining serum and dialysis effluent samples. c12 anuric cases are excluded.