International Journal of Nephrology / 2019 / Article / Tab 3

Research Article

Urinary Uromodulin Levels and UMOD Variants in Black South Africans with Hypertension-Attributed Chronic Kidney Disease

Table 3

Relationship between rs13333226 polymorphisms in the UMOD gene and clinical and demographic features in CKD cases.

rs13333226AAAGGGp-value#

N (%)253115
Gender (M/F)15/1019/1212/30.379
Age, years44 (40-50)49 (44-53)47 (42-57)0.157
Systolic BP, mmHg141 (128-166)151 (135-170)138 (130-141)0.327
Diastolic BP, mmHg87 (78-97)90 (79-100)82 (76-87)0.333
Serum creatinine, µmol/L823 (505-1141)638 (513-1054)810 (462-1015)0.790
CKD-EPI eGFR, ml/min per 1.73 m26 (4-12)9 (4-11)7 (5-13)0.833
Uric acid, mmol/L0.4 (0.4-0.6)0.5 (0.4-0.6)0.5 (0.4-0.5)0.666
Urine PCR g/mmol0.1 (0.1-0.2)0.1 (0.1-0.2)0.1 (0.0-0.2)0.315
Log Uromodulin concentration (µg/ml), mean (SD)0.3 ± 1.9-0.5 ± 1.76-1.4 ± 1.7

Data given as median (interquartile range) unless specified.
P values: #Kruskal-Wallis unless specified; earson’s chi square; tests.
BP, blood pressure; eGFR, estimated glomerular filtration rate; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; PCR, protein: creatinine ratio.

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