No Race-Ethnicity Adjustment in CKD-EPI Equations Is Required for Estimating Glomerular Filtration Rate in the Brazilian Population
Table 4
Distribution of patients according to KDIGO classification of CKD staging, based on mGFR and eGFR, and the concordance rate of CKD staging between eGFR and mGFR.
Method of GFR analysis
All (n = 100)
White (n = 39)
African Brazilian (n = 61)
mGFR (51Cr-EDTA)
CKD stage
G1
9 (9.0%)
2 (5.1%)
7 (11.5%)
G2
18 (18.0%)
5 (12.8%)
13 (21.3%)
G3a
19 (19.0%)
9 (23.1%)
10 (16.4%)
G3b
17 (17.0%)
7 (17.9%)
10 (16.4%)
G4
24 (24.0%)
11 (28.2%)
13 (21.3%)
G5
13 (13.0%)
5 (12.8%)
8 (13.1%)
eGFRCr (no race adjustment)
CKD stage
G1
12 (12.0%)
4 (10.3%)
8 (13.1%)
G2
18 (18.0%)
5 (12.8%)
13 (21.3%)
G3a
14 (14.0%)
4 (10.3%)
10 (16.4%)
G3b
20 (20.0%)
10 (25.6%)
10 (16.4%)
G4
25 (25.0%)
14 (35.9%)
11 (18.0%)
G5
11 (11.0%)
2 (5.1%)
9 (14.8%)
Concordance with mGFR (%)
56.0 (46.2–65.3)
59.0 (43.4–72.9)
54.1 (41.7–66.0)
eGFRCr (with race adjustment)
CKD stage
G1
17 (17.0%)
—
15 (24.6%)
G2
16 (16.0%)
—
9 (14.8%)
G3a
14 (14.0%)
—
10 (16.4%)
G3b
20 (20.0%)
—
10 (16.4%)
G4
26 (26.0%)
—
12 (19.7%)
G5
7 (7.0%)
—
5 (8.2%)
Concordance with mGFR (%)
55.0 (45.2–64.4)
52.5 (40.2–64.5)
eGFRCr-Cys (no race adjustment)
CKD stage
G1
10 (10.0%)
3 (7.7%)
7 (11.5%)
G2
20 (20.0%)
6 (15.4%)
14 (23.0%)
G3a
8 (8.0%)
2 (5.1%)
6 (9.8%)
G3b
25 (25.0%)
10 (25.6%)
15 (24.6%)
G4
29 (29.0%)
15 (38.5%)
14 (23.0%)
G5
8 (8.0%)
3 (7.7%)
5 (8.2%)
Concordance with mGFR (%)
64.0 (54.2–72.7)
66.7 (50.9–79.4)
62.3 (49.7–73.4)
eGFRCr-Cys (with race adjustment)
CKD stage
G1
14 (14.0%)
—
11 (18.0%)
G2
16 (16.0%)
—
10 (16.4%)
G3a
12 (12.0%)
—
10 (16.4%)
G3b
22 (22.0%)
—
12 (19.7%)
G4
29 (29.0%)
—
14 (23.0%)
G5
7 (7.0%)
—
4 (6.6%)
Concordance with mGFR (%)
62.0 (52.2–70.9)
59.0 (46.5–70.5)
mGFR: measured glomerular filtration rate; eGFR: estimated glomerular filtration rate; Cr: creatinine; Cys: cystatin C. Frequencies are expressed by number (percentage), and concordance between CKD stages as percentage (95% confidence interval).
