No Race-Ethnicity Adjustment in CKD-EPI Equations Is Required for Estimating Glomerular Filtration Rate in the Brazilian Population
Table 5
Performance of the equations for estimation of GFR.
eGFRCr (no race adjustment)
eGFRCr (with race adjustment)
eGFRCr-Cys (no race adjustment)
eGFRCr-Cys (with race adjustment)
Bias (mL/min/1.73 m2)
All participants
0.1 (−6.5–7.1)
2.8 (−1.9–11.0)
−0.1 (−6.2–4.0)
1.6 (−3.7–5.5)
White
0.7 (−5.6–7.8)
—
0.4 (−5.6–4.8)
—
African Brazilian
−0.5 (−8.1–5.9)
3.2 (−0.5–14.3)
−0.2 (−7.1–3.0)
2.4 (−2.2–5.8)
Precision (mL/min/1.73 m2)
All participants
6.8 (3.2–11.9)
6.3 (2.2–12.2)
5.1 (2.0–10.7)
4.5 (2.3–10.3)
White
6.3 (3.5–11.1)
—
4.8 (2.1–8.4)
—
African Brazilian
7.4 (3.0–13.3)
5.5 (2.0–14.3)
5.5 (2.0–11.4)
4.3 (2.4–11.8)
Accuracy (P30)
All participants
79.0 (70.0–85.9)
74.0 (64.6–81.6)
83.0 (74.3–89.2)
82.0 (73.2–88.4)
White
84.6 (69.9–93.1)
—
87.2 (72.8–94.9)
—
African Brazilian
75.4 (63.2–84.6)
67.2 (54.7–77.7)
80.3 (68.5–88.5)
78.7 (66.7–87.2)
eGFR: estimated glomerular filtration rate; Cr: creatinine; Cys: cystatin C. Bias and precision are expressed as median (interquartile range), and accuracy as percentage (95% confidence interval). vs. eGFRCr without race adjustment and eGFRCr-Cys without race adjustment; vs. eGFRCr-Cys without race adjustment; vs. eGFRCr without race adjustment; vs. eGFRCr with race adjustment.
