No Race-Ethnicity Adjustment in CKD-EPI Equations Is Required for Estimating Glomerular Filtration Rate in the Brazilian Population
Table 6
Performance of the equations according to the range of measured GFR using the threshold of 60 mL/min/1.73 m2.
eGFRCr (no race adjustment)
eGFRCr (with race adjustment)
eGFRCr-Cys (no race adjustment)
eGFRCr-Cys (with race adjustment)
GFR ≥ 60 mL/min/1.73 m2 (n = 27)
Bias (mL/min/1.73 m2)
−4.0 (−11.3–14.6)
5.5 (−2.6–21.8)
−3.6 (−11.8–10.2)
2.4 (−3.8–15.5)
Precision (mL/min/1.73 m2)
12.1 (8.3–19.7)
11.6 (4.2–21.8)
11.0 (5.5–20.0)
8.7 (3.1–17.3)
Accuracy (P30)
85.2 (66.9–94.7)
77.8 (58.9–89.7)
85.2 (66.9–94.7)
88.9 (71.1–97.0)
GFR < 60 mL/min/1.73 m2 (n = 73)
Bias (mL/min/1.73 m2)
0.1 (−4.9–6.4)
1.8 (−1.8–7.4)
0.1 (−4.1–2.4)
1.5 (−3.6–3.7)
Precision (mL/min/1.73 m2)
5.5 (1.6–9.2)
5.6 (1.8–10.5)
3.4 (1.7–8.2)
3.5 (2.2–7.8)
Accuracy (P30)
76.7 (65.7–85.0)
72.6 (61.4–81.6)
82.2 (71.7–89.4)
79.5 (68.7–87.2)
eGFR: estimated glomerular filtration rate; Cr: creatinine; Cys: cystatin C. Bias and precision are expressed as median (interquartile range), and accuracy as percentage (95% confidence interval). vs. eGFRCr without race adjustment and eGFRCr-Cys without race adjustment; vs. eGFRCr-Cys without race adjustment.
