Research Article

Comparing the Efficacy and Safety of Induction Therapies for the Treatment of Patients with Proliferative Lupus Nephritis in South Africa

Table 3

: Complete, partial remission and relapse in the two groups after therapy.

IVCYC OR (95% CI)MMF OR (95% CI)Total OR (95% CI) value

CR at 6 months18.0 (8.6–31.4)25.0 (7.3–52.4)19.7 (10.9–31.3)0.54
PR at 6 months58.0 (43.2–71.8)62.5 (35.4–84.8)59.1 (46.3–71.0)0.75
CR + PR76.0 (61.8–86.9)87.5 (61.6–98.4)78.8 (67.0–87.9)0.33
Relapse at 12 months8.1 (1.7–21.9)10.3 (4.3–48.1)11.5 (4.3–23.4)0.22

value for comparison between IVCYC and MMF; CR = complete remission; PR = partial remission; OR: odds ratio; IVCYC: intravenous cyclophosphamide; MMF: mycophenolate mofetil.