A Comparison of Urine Dilution Ability between Adult Dominant Polycystic Kidney Disease, Other Chronic Kidney Diseases, and Healthy Control Subjects: A Case-Control Study

Figure 1

CH2O (a), u-AQP2 excretion rate (b), FENa (c), and u-ENaC excritoin rate (d) during urine dilution test in patients with adult dominant polycystic kidney disease (ADPKD), patients with non-ADPKD kidney disease (non-ADPKD), and healthy control subjects (controls). An oral water load of 20 ml/body weight was given immediately after Period 2. Urine was collected in seven periods. Period 1 (24 hours): from 07.30 AM the day before arrival to the laboratory to 07.30 AM on the examination day. Period 2 (one hour): 07.30–08.30 AM. Period 3 (one hour): 08.30–09.30 AM. Period 4 (one hour): 09.30–11.30 AM. Period 5 (one hour): 10.30–11.30 AM. Period 6 (one hour): 11.30–00.30 PM. Period 7 (on hour): 00.30–01.30 PM. Values represent mean. between ADPKD and Non-ADPKD patients. (a). Values represent median between ADPKD and/or non-ADPKD patients and healthy controls (b). Values represent mean. between ADPKD and/or non-ADPKD patients and healthy controls (c). Values represent median between ADPKD and/or non-ADPKD patients and healthy controls (d).

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