Research Article

Serum Sclerostin, Body Composition, and Sarcopenia in Hemodialysis Patients with Diabetes

Table 1

Clinical characteristics of the study patients.

VariablePatients value
With diabetesWithout diabetes

Gender
 Male26 (63.4%)32 (62.7%)
 Female15 (36.6%)19 (37.3%)0.947
Age (yr)64.3 ± 10.362.5 ± 15.80.522
Diabetes duration (yr)
 3–5 years1 (2.4%)0 (0.0%)
 >5 years40 (97.6%)0 (0.0%)
Time since diagnosis of CKD
 <3 years17 (41.5%)11 (21.6%)
 3–5 years6 (14.6%)9 (17.6%)
 >5 years18 (43.9%)31 (60.8%)0.117
Time in hemodialysis
 <3 years31 (75.6%)30 (58.8%)
 3–5 years6 (14.6%)9 (17.6%)
 >5 years4 (9.8%)12 (23.5%)0.168
Systolic pressure (mmHg)146.3 ± 21.3136.3 ± 21.50.028
Diastolic pressure (mmHg)70.2 ± 10.869.4 ± 14.80.756
Weight (kg)74.3 ± 14.868.0 ± 11.70.024
Height (cm)167.1 ± 7.2168.0 ± 9.70.598
BMI (kg/m2)26.6 ± 5.224.1 ± 3.70.010
WC (cm)103.1 ± 12.294.9 ± 10.70.001
HC (cm)105.0 ± 10.3100.2 ± 7.10.012
WHR1.0 ± 0.10.9 ± 0.10.021
Serum sclerostin (pmol/l)97.2 ± 46.679.7 ± 31.20.044

CKD, chronic kidney disease; BMI, body mass index; WC, circumference waist; HC, hip circumference; WHR, waist hip ratio.