Bidirectional Interaction of Thyroid-Kidney Organs in Disease States

Figure 2

Distribution of patients with primary hypothyroidism, elevated serum CPK, serum creatinine, and total cholesterol in different stages of decreased eGFR. The first top line shows elevated serum TSH greater than or equal to 10 mIU/ml (solid quadrangle), second line is indicative of elevated serum creatinine greater than or equal to 1.1–1.3 mg/dl (solid square) that forms overlapped line with elevated serum TSH, third line is indicative of elevated total cholesterol (cross mark), and the fourth bottom line is indicative of raised creatine phosphokinase (solid triangle). CPK, creatine phosphokinase; eGFR, estimated glomerular filtration rate; SCr, serum creatinine; TSH, thyroid-stimulating hormone.