Value of Urinary Neutrophil Gelatinase-Associated Lipocalin versus Conventional Biomarkers in Predicting Response to Treatment of Active Lupus Nephritis

Table 4

Comparison between complete responders with partial and nonresponders as regards to baseline renal biomarkers.

Variable	Complete responders (N = 13)	Partial and nonresponders (N = 27)	Test value	value
	Mean ± SD	Mean ± SD
C3	68.23 ± 24.93 mg/dL	61.81 ± 16.68 mg/dL	−0.966	0.340
C4	16.54 ± 5.46 mg/dL	16.85 ± 4.12 mg/dL	0.203	0.841
Creatinine	1.76 ± 0.97 mg/dL	2.95 ± 0.68 mg/dL	4.486	0.0001
eGFR	63.69 ± 36.07 mL/min/1.73 m^2	31.00 ± 7.36 mL/min/1.73 m^2	−4.575	0.0001
Pr/Cr ratio	3.95 ± 1.65 mg/mg	2.38 ± 0.91 mg/mg	−3.884	0.0001
UNGAL	17.35 ± 7.22 ng/mL	39.55 ± 16.28 ng/mL	4.675	0.0001

Student’s t-test: significant at 0.05 level. C3, complement component 3; C4, complement component 4; eGFR, estimated glomerular filtration rate; Pr/Cr ratio, protein-to-creatinine ratio; UNGAL, urinary neutrophil gelatinase-associated lipocalin.