Value of Urinary Neutrophil Gelatinase-Associated Lipocalin versus Conventional Biomarkers in Predicting Response to Treatment of Active Lupus Nephritis

Table 5

Cutoff levels for baseline UNGAL and conventional biomarkers in predicting renal response to induction.

Variable	AUC	Cutoff point	Sensitivity	Specificity	PPV	NPV
Creatinine	0.853	1.9 mg/dL	76.92	92.59	83.3	89.3
eGFR	0.806	36 mL/min/1.73 m^2	84.62	77.78	64.7	91.3
Pr/Cr ratio	0.802	3 mg/mg	76.92	77.78	62.5	87.5
UNGAL	0.943	26.5 ng/mL	92.31	88.89	80.0	96.0

eGFR, estimated glomerular filtration rate; Pr/Cr ratio, protein-to-creatinine ratio; UNGAL, urinary neutrophil gelatinase-associated lipocalin.