Value of Urinary Neutrophil Gelatinase-Associated Lipocalin versus Conventional Biomarkers in Predicting Response to Treatment of Active Lupus Nephritis

Table 6

Comparison between complete responders with partial and nonresponders as regards three-month follow-up renal biomarkers.

Variable	Complete responders (N = 13)	Partial and nonresponders (N = 27)	Test value	value
	Mean ± SD	Mean ± SD
C3	101.15 ± 22.27 mg/dL	91.48 ± 18.66 mg/dL	−1.442	0.157
C4	26.15 ± 5.51 mg/dL	26.67 ± 5.22 mg/dL	0.286	0.776
Creatinine	1.12 ± 0.24 mg/dL	2.53 ± 0.81 mg/dL	6.107	0.0001
eGFR	80.15 ± 24.09 mL/min/1.73 m^2	36.59 ± 10.63 mL/min/1.73 m^2	−7.994	0.0001
Pr/Cr ratio	1.52 ± 0.68 mg/mg	1.38 ± 0.58 mg/mg	−0.701	0.487
UNGAL	13.38 ± 5.83 ng/mL	35.23 ± 13.47 ng/mL	5.576	0.0001

Student’s t-test: significant at 0.05 level. C3, complement component 3; C4, complement component 4; eGFR, estimated glomerular filtration rate; Pr/Cr ratio, protein-to-creatinine ratio; UNGAL, urinary neutrophil gelatinase-associated lipocalin.