Research Article
The Implication of Dropping Race from the MDRD Equation to Estimate GFR in an African American-Only Cohort
| | Characteristics | Total (N = 327) | Chronic kidney disease glomerular stage by MDRD formula | value | | G1/2 (N = 183) | G3a (N = 85) | G3b (N = 37) | G4 (N = 22) |
| | Age (year) | 61.9 ± 14.2 | 58.6 ± 14.4 | 65.7 ± 12.5 | 66.2 ± 13.9 | 68.1 ± 11.5 | 0.0002 | | Female sex (%) | 60.6 | 61.7 | 60.0 | 56.8 | 59.1 | 0.811 | | Body mass index (kg/m2) | 29.7 ± 6.8 | 29.9 ± 7.0 | 29.4 ± 6.6 | 30.8 ± 6.4 | 27.1 ± 6.2 | 0.218 | | GFR, ml/min/1.73 m2 | 67.4 ± 27.2 | 86.2 ± 19.8 | 52.4 ± 4.4 | 37.0 ± 4.3 | 20.2 ± 3.5 | <0.0001 | | Medical history (%) | | | | | | | | Hypertension | 94.2 | 92.9 | 97.6 | 89.2 | 100 | 0.141 | | Diabetes | 57.5 | 57.4 | 55.3 | 73.0 | 40.9 | 0.099 | | Congestive heart failure | 19.3 | 19.7 | 21.2 | 16.2 | 13.6 | 0.828 | | Stroke | 13.5 | 15.8 | 8.2 | 8.1 | 22.7 | 0.143 | | Coronary artery disease | 24.5 | 24.6 | 22.4 | 35.1 | 13.6 | 0.274 | | Dyslipidemia | 63.3 | 60.7 | 67.1 | 64.9 | 68.2 | 0.721 |
| | Etiology of CKD (%) | | | | | | | | Hypertensive nephrosclerosis | 59.6 | 54.6 | 67.1 | 59.5 | 72.7 | 0.144 | | Diabetic kidney disease | 37.9 | 38.8 | 32.9 | 45.9 | 36.4 | 0.574 | | Glomerulonephritis | 7.6 | 9.8 | 5.9 | 2.7 | 4.5 | 0.362 | | Polycystic kidney disease | 4.3 | 4.4 | 3.5 | 2.7 | 9.1 | 0.662 | | Others | 24.2 | 26.8 | 22.4 | 21.6 | 13.6 | 0.514 |
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