Evaluation of Renoprotective Effects of Our Locally Grown Green Coffee Beans against Cisplatin-Induced Nephrotoxicity in Swiss Albino Mice

Table 1

Serum creatinine and BUN levels of mice.

Variables (mg/dl)	Groups					value
	I	II	III	IV	V
Serum creatinine	0.64 ± 0.05	0.99 ± 0.11^abcd	0.74 ± 0.06	0.71 ± 0.08	0.68 ± 0.07	≤0.001
Serum BUN	39.8 ± 1.3	56.7 ± 6.8^abcd	44.1 ± 4.8	42.1 ± 3.5	41.6 ± 2.5	≤0.001

The values were expressed as mean ± SE. The sample size is 6 for each group. I: normal control group; II: negative control group; III: received 100 mg/kg/day green coffee beans; IV: received 200 mg/kg/day of green coffee beans; and V: received 300 mg/kg/day of green coffee beans, respectively. indicates significant differences among all groups at as tested by one-way ANOVA. Superscript letters (a, b, c, and d) indicate significant differences compared to groups I, III, IV, and V, respectively at as tested by Tukey post hoc multiple comparisons.