Efficacy of Weekly Split versus Single Doses of Ergocalciferol on Serum 25-Hydroxyvitamin D among Patients on Continuous Ambulatory Peritoneal Dialysis: A Randomized Controlled Trial
Table 2
Outcomes between split and single dose of ergocalciferol 60,000 IU weekly supplement at 8 weeks.
Parameters
Split dose of ergocalciferol (N = 25)
Single dose of ergocalciferol (N = 25)
valueB
Baseline
At 8 weeks
Mean change
Baseline
At 8 weeks
Mean change
Serum 25(OH)D (ng/mL)
22.7 ± 5.9
29.5 ± 9.5A
6.8 ± 10.5
22.9 ± 5.3
31.2 ± 12.3A
8.4 ± 11.9
0.561
Serum calcium (mg/dL)
9.2 ± 0.7
9.5 ± 0.6
0.3 ± 0.7
9.1 ± 0.5
9.3 ± 0.6
0.3 ± 0.8
0.276
Serum phosphate (mg/dL)
4.7 ± 1.4
4.5 ± 1.1
−0.2 ± 1.5
4.3 ± 1.2
4.2 ± 1.1
−0.2 ± 1.2
0.912
Intact parathyroid hormone (pg/mL)
266.7 ± 255.6
220.0 ± 172.9
46.7 ± 188.7
270.0 ± 188.1
260.2 ± 175.7
−9.9 ± 114.3
0.206
Data in the table are shown with average ± standard deviation. 25(OH)D, 25-hydroxyvitamin D. A value < 0.05 vs. baseline. B value of mean change between the two groups.