Efficacy of Weekly Split versus Single Doses of Ergocalciferol on Serum 25-Hydroxyvitamin D among Patients on Continuous Ambulatory Peritoneal Dialysis: A Randomized Controlled Trial

Table 2

Outcomes between split and single dose of ergocalciferol 60,000 IU weekly supplement at 8 weeks.

Parameters	Split dose of ergocalciferol (N = 25)			Single dose of ergocalciferol (N = 25)			value^B
	Baseline	At 8 weeks	Mean change	Baseline	At 8 weeks	Mean change
Serum 25(OH)D (ng/mL)	22.7 ± 5.9	29.5 ± 9.5^A	6.8 ± 10.5	22.9 ± 5.3	31.2 ± 12.3^A	8.4 ± 11.9	0.561
Serum calcium (mg/dL)	9.2 ± 0.7	9.5 ± 0.6	0.3 ± 0.7	9.1 ± 0.5	9.3 ± 0.6	0.3 ± 0.8	0.276
Serum phosphate (mg/dL)	4.7 ± 1.4	4.5 ± 1.1	−0.2 ± 1.5	4.3 ± 1.2	4.2 ± 1.1	−0.2 ± 1.2	0.912
Intact parathyroid hormone (pg/mL)	266.7 ± 255.6	220.0 ± 172.9	46.7 ± 188.7	270.0 ± 188.1	260.2 ± 175.7	−9.9 ± 114.3	0.206

Data in the table are shown with average ± standard deviation. 25(OH)D, 25-hydroxyvitamin D. ^A value < 0.05 vs. baseline. ^B value of mean change between the two groups.