Anti-Factor H Antibodies in Egyptian Children with Hemolytic Uremic Syndrome
Table 2
Laboratory data of HUS patients.
Parameter
Typical aHUS (n = 22)
Anti-FH-positive aHUS (n = 12)
Anti-FH-negative aHUS (n = 16)
Hb (g/dL)
6.6 ± 1.5
7 ± 0.7
7.1 ± 1.2
p value
WBCs (10 ̂3/cmm)
14.3 ± 5.3
10.7 ± 3.4
10.5 ± 4.9
p value
PLT (10̂ ̂3/cmm)
98.7 ± 54.4
79.1 ± 34
101.6 ± 46.2
p value
LDH (U/L)
2031.8 ± 1080.5
2020.2 ± 1263.7
1305.4 ± 1038.1
p value
Bilirubin (mg/dL)
0.89 ± 0.069
1.3 ± 1
0.93 ± 1.3
p value
Reticulocytes (%)
4.8 ± 2.1
5.8 ± 1.9
4.2 ± 2.2
p value
Creatinine (mg/dL)
6.8 ± 4.7
6.2 ± 4.6
5.9 ± 3.5
p value
BUN (mg/dL)
121.1 ± 80.8
126.6 ± 58.6
111.1 ± 60.5
p value
Albumin (g/dL)
3.1 ± 0.48
3.2 ± 0.6
2.9 ± 0.85
p value
Low C3 (normal 80–160 mg/dL)
—
3 (25%)
2 (12.5%)
Low C4 (normal 20–40 mg/dL)
—
3 (25%)
5 (31.3%)
Low CFH (normal 70–130 ug/mL)
—
2 (17%)
4 (25%)
Hb: hemoglobin; WBC: white blood cells; PLT: platelets; LDH; lactate dehydrogenase; BUN: blood urea nitrogen; CFH: complement factor H. Data are presented as the mean ± standard deviation or the number of patients with the percentage in brackets. Bold values are significant at . Analysis was done using t-test and chi-square test.
