Bevacizumab Increases Endothelin-1 Production via Forkhead Box Protein O1 in Human Glomerular Microvascular Endothelial Cells In Vitro

<div>A schematic showing signaling pathways that increase ET-1 production on FoxO1 nuclear localization induced by bevacizumab in human glomerular microvascular endothelial cells (hGECs). Abbreviations: VEGFA, vascular endothelial growth factor A; Akt, protein kinase B; FoxO1, forkhead box protein O1; ET-1, endothelin-1.</div>

International Journal of Nephrology

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Figure 5

Figure 5: Bevacizumab Increases Endothelin-1 Production via Forkhead Box Protein O1 in Human Glomerular Microvascular Endothelial Cells In Vitro 