PAC-Mediated AKI Protection Is Critically Mediated but Does Not Exclusively Depend on Cell-Derived Microvesicles

Figure 4

Peritubular capillary density (PTCD) of all groups. The PTCD surprisingly decreased if MV from native PACs were administered (either alone or in combination with the secretome). Other significant differences were missing. (a–d) The respective results of all preconditioning groups ((a) Ang-1; (b) Ang-2; (c) BMP-5; (d) melatonin). (e–g) Representative images of three groups (labelled) ((e–g) magnification ×40; value as compared to “IRI” <0.05; results as means ± SEM).

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