Early, Noninvasive Clinical Indicators of Kidney Prognosis in Primary Nephrotic Syndrome: A Retrospective Exploratory Study

Table 5

Cutoff values of predictive factors for intractable NS.

Clinical parameters	AUC [95% CI]	Cutoff value (sensitivity, specificity)
Δs-suPAR (2M; pg/mL)	0.84 [0.65–1.00]	93.5 (0.76, 0.86)
u-PCR (2M; g/gCr)	0.98 [0.93–1.00]	1.1 (0.97, 1.00)
u-L-FABP (2M; μg/gCr)	0.78 [0.59–0.96]	4.1 (0.59, 1.00)
s-suPAR (2M; pg/mL)	0.85 [0.72–0.99]	3297.0 (0.79, 0.86)

Δs-suPAR (2M), change (Δ) in the serum soluble urokinase plasminogen activator receptor (suPAR) within the first 2 months of immunosuppressive therapy (IST); u-PCR (2M), urinary protein-to-creatinine ratio at 2 months after initiating IST; u-L-FABP (2M), urinary liver-type fatty acid-binding protein at 2 months after initiating IST; s-suPAR (2M), serum suPAR at 2 months after initiating IST; AUC, the area under the ROC curve; 95% CI, 95% confidence interval.