Prognostic and Diagnostic Value of Endocan in Kidney Diseases
Table 1
Benefits and limitations of endocan as a prognostic and diagnostic biomarker in kidney diseases.
Benefits
Soluble in human fluids
Having low concentration in physiological conditions
Easily measurable
Noninvasive
Multifunctional, associated with inflammation, endothelial injury, the decline of renal function, and/or incidence of cardiovascular events in several types of kidney disease
Limitations
Plasma elevation does not always correlate with kidney function deterioration
Several medications could influence its measurement
Large-scaled, multicentered clinical trials pend to define its applicability