Review Article

Prognostic and Diagnostic Value of Endocan in Kidney Diseases

Table 1

Benefits and limitations of endocan as a prognostic and diagnostic biomarker in kidney diseases.

Benefits
 Soluble in human fluids
 Having low concentration in physiological conditions
 Easily measurable
 Noninvasive
 Multifunctional, associated with inflammation, endothelial injury, the decline of renal function, and/or incidence of cardiovascular events in several types of kidney disease

Limitations
 Plasma elevation does not always correlate with kidney function deterioration
 Several medications could influence its measurement
 Large-scaled, multicentered clinical trials pend to define its applicability