Research Article

Diagnostic Accuracy of Direct Immunofluorescence Test on Paraffin-Embedded Blocks in Comparison with Frozen Section Blocks in Renal Biopsies

Table 7

Comparison of immunofluorescence intensity on fresh frozen and paraffin-embedded renal biopsies.

DiseaseNumber of cases with no difference in intensity of diagnostic immunoglobulin/complement (%) IF-F = IF-PNumber of cases with the difference in intensity of diagnostic immunoglobulin/complement (%) IF-F > IF-PTotal number of cases
Difference of 1+Difference of 2+

Membranous nephropathy22 (84.6%)4 (15.3%)26
Lupus nephritis11 (61%)7 (38%)18
IgA nephropathy4 (57.1%)2 (28.5%)1 (14.2%)7

IF-F: Immunofluorescence on fresh frozen tissue: IF-P: Immunofluorescence on paraffin-embedded tissue.