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International Journal of Optics
Volume 2012, Article ID 724024, 13 pages
http://dx.doi.org/10.1155/2012/724024
Research Article

Megavoltage X-Ray Imaging Based on Cerenkov Effect: A New Application of Optical Fibres to Radiation Therapy

A. Teymurazyan1 and G. Pang1,2,3,4

1Imaging Research, Sunnybrook Health Sciences Centre and Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada M4N 3M5
2Odette Cancer Centre, Toronto, ON, Canada M4N 3M5
3Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada M5G 2M9
4Department of Physics, Ryerson University, Toronto, ON, Canada M5B 2K3

Received 14 July 2011; Revised 19 September 2011; Accepted 20 September 2011

Academic Editor: Baohong Yuan

Copyright © 2012 A. Teymurazyan and G. Pang. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. F. M. Khan, The Physics of Radiation Therapy, Williams & Wilkins, Baltimore, Md, USA, 2nd edition, 1994.
  2. E. J. Seppi, P. Munro, S. W. Johnsen et al., “Megavoltage cone-beam computed tomography using a high-efficiency image receptor,” International Journal of Radiation Oncology Biology Physics, vol. 55, no. 3, pp. 793–803, 2003. View at Publisher · View at Google Scholar · View at Scopus
  3. J. Pouliot, A. Bani-Hashemi, J. Chen et al., “Low-dose megavoltage cone-beam CT for radiation therapy,” International Journal of Radiation Oncology Biology Physics, vol. 61, no. 2, pp. 552–560, 2005. View at Publisher · View at Google Scholar · View at Scopus
  4. L. E. Antonuk, “Electronic portal imaging devices: a review and historical perspective of contemporary technologies and research,” Physics in Medicine and Biology, vol. 47, no. 6, pp. R31–R65, 2002. View at Google Scholar · View at Scopus
  5. G. Pang and J. A. Rowlands, “Development of high quantum efficiency flat panel detectors for portal imaging: Intrinsic spatial resolution,” Medical Physics, vol. 29, no. 10, pp. 2274–2285, 2002. View at Publisher · View at Google Scholar · View at Scopus
  6. M. A. Mosleh-Shirazi, P. M. Evans, W. Swindell, J. R. N. Symonds-Tayler, S. Webb, and M. Partridge, “Rapid portal imaging with a high-efficiency, large field-of-view detector,” Medical Physics, vol. 25, no. 12, pp. 2333–2346, 1998. View at Publisher · View at Google Scholar · View at Scopus
  7. J. Ostling, M. Wallmark, A. Brahme et al., “Novel detector for portal imaging in radiation therapy,” in Medical Imaging 2000: Physics of Medical Imaging, vol. 3977 of Proceedings of SPIE, pp. 84–95, February 2000. View at Scopus
  8. R. Hinderer, J. M. Kapatoes, H. Keller et al., “Development of a new multielement detector system for megavoltage photons,” in Medical Imaging 2002: Physics of Medical Imaging, vol. 4682 of Proceedings of SPIE, pp. 809–818, February 2002. View at Publisher · View at Google Scholar · View at Scopus
  9. A. Sawant, L. E. Antonuk, Y. El-Mohri et al., “Segmented crystalline scintillators: an initial investigation of high quantum efficiency detectors for megavoltage x-ray imaging,” Medical Physics, vol. 32, no. 10, pp. 3067–3083, 2005. View at Publisher · View at Google Scholar · View at Scopus
  10. T. T. Monajemi, B. G. Fallone, and S. Rathee, “Thick, segmented CdWO4-photodiode detector for cone beam megavoltage CT: a Monte Carlo study of system design parameters,” Medical Physics, vol. 33, no. 12, pp. 4567–4577, 2006. View at Publisher · View at Google Scholar · View at Scopus
  11. Y. El-Mohri, L. E. Antonuk, Q. Zhao et al., “Low-dose megavoltage cone-beam CT imaging using thick, segmented scintillators,” Physics in Medicine and Biology, vol. 56, pp. 1509–1527, 2011. View at Google Scholar
  12. G. Pang and J. A. Rowlands, “Development of high quantum efficiency, flat panel, thick detectors for megavoltage x-ray imaging: a novel direct-conversion design and its feasibility,” Medical Physics, vol. 31, no. 11, pp. 3004–3016, 2004. View at Publisher · View at Google Scholar · View at Scopus
  13. S. Wang, J. K. Gardner, J. J. Gordon et al., “Monte Carlo-based adaptive EPID dose kernel accounting for different field size responses of imagers,” Medical Physics, vol. 36, no. 8, pp. 3582–3595, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. D. A. Jaffray, J. J. Battista, A. Fenster, and P. Munro, “Monte Carlo studies of x-ray energy absorption and quantum noise in megavoltage transmission radiography,” Medical Physics, vol. 22, no. 7, pp. 1077–1088, 1995. View at Publisher · View at Google Scholar · View at Scopus
  15. X. Mei, J. A. Rowlands, and G. Pang, “Electronic portal imaging based on Cerenkov radiation: a new approach and its feasibility,” Medical Physics, vol. 33, no. 11, pp. 4258–4270, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. J. V. Jelley, Cerenkov Radiation and Its Applications, Pergamon Press, London, UK, 1958.
  17. J. A. Rowlands and J. Yorkston, “Flat Panel Detectors for Digital Radiography,” in Handbook of Medical Imaging, L. V. M. Richard, B. Jacob, and L. K. Harold, Eds., pp. 223–328, SPIE Press, 2000. View at Google Scholar
  18. J. M. Boudry and L. E. Antonuk, “Radiation damage of amorphous silicon, thin-film, field-effect transistors,” Medical Physics, vol. 23, no. 5, pp. 743–754, 1996. View at Publisher · View at Google Scholar · View at Scopus
  19. K. Tanioka, J. Yamazaki, K. Shidara et al., “Avalanche-mode amorphous selenium photoconductive target for camera tube,” in Advances in Electronics and Electron Physics, B. L. Morgan, Ed., vol. 74, pp. 379–387, Academic Press, 1988. View at Google Scholar
  20. S. Agostinelli, J. Allison, K. Amako et al., “GEANT4—a simulation toolkit,” Nuclear Instruments and Methods in Physics Research A, vol. 506, no. 3, pp. 250–303, 2003. View at Publisher · View at Google Scholar · View at Scopus
  21. J. T. Dobbins, “Effects of undersampling on the proper interpretation of modulation transfer function, noise power spectra, and noise equivalent quanta of digital imaging systems,” Medical Physics, vol. 22, no. 2, pp. 171–182, 1995. View at Publisher · View at Google Scholar · View at Scopus
  22. F. Cremers, T. Frenzel, C. Kausch, D. Albers, T. Schönborn, and R. Schmidt, “Performance of electronic portal imaging devices (EPIDs) used in radiotherapy: image quality and dose measurements,” Medical Physics, vol. 31, no. 5, pp. 985–996, 2004. View at Publisher · View at Google Scholar · View at Scopus
  23. H. Fujita, D. Y. Tsai, T. Itoh et al., “A simple method for determining the modulation transfer function in digital radiography,” IEEE Transactions on Medical Imaging, vol. 11, no. 1, pp. 34–39, 1992. View at Publisher · View at Google Scholar · View at Scopus
  24. D. A. Jaffray, J. J. Battista, A. Fenster, and P. Munro, “X-ray scatter in megavoltage transmission radiography: Physical characteristics and influence on image quality,” Medical Physics, vol. 21, no. 1, pp. 45–60, 1994. View at Publisher · View at Google Scholar · View at Scopus
  25. R. K. Swank, “Absorption and noise in x-ray phosphors,” Journal of Applied Physics, vol. 44, no. 9, pp. 4199–4203, 1973. View at Publisher · View at Google Scholar · View at Scopus
  26. C. E. Dick and J. W. Motz, “Image information transfer properties of x-ray fluorescent screens,” Medical Physics, vol. 8, no. 3, pp. 337–346, 1981. View at Publisher · View at Google Scholar · View at Scopus
  27. M. Lachaîne and B. G. Fallone, “Monte Carlo detective quantum efficiency and scatter studies of a metal/a-Se portal detector,” Medical Physics, vol. 25, no. 7, pp. 1186–1194, 1998. View at Publisher · View at Google Scholar · View at Scopus
  28. B. M. C. McCurdy, K. Luchka, and S. Pistorius, “Dosimetric investigation and portal dose image prediction using an amorphous silicon electronic portal imaging device,” Medical Physics, vol. 28, no. 6, pp. 911–924, 2001. View at Google Scholar · View at Scopus