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International Journal of Optics
Volume 2016, Article ID 1370259, 12 pages
Research Article

The Impact of Pixel Resolution, Integration Scale, Preprocessing, and Feature Normalization on Texture Analysis for Mass Classification in Mammograms

1Departament d’Enginyeria Informàtica i Matemàtiques, Universitat Rovira i Virgili, Avinguda Paisos Catalans 26, 43007 Tarragona, Spain
2Department of Radiology, Radboud University Medical Center, 6525 GA Nijmegen, Netherlands

Received 6 November 2015; Revised 21 March 2016; Accepted 22 March 2016

Academic Editor: Chenggen Quan

Copyright © 2016 Mohamed Abdel-Nasser et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Texture analysis methods are widely used to characterize breast masses in mammograms. Texture gives information about the spatial arrangement of the intensities in the region of interest. This information has been used in mammogram analysis applications such as mass detection, mass classification, and breast density estimation. In this paper, we study the effect of factors such as pixel resolution, integration scale, preprocessing, and feature normalization on the performance of those texture methods for mass classification. The classification performance was assessed considering linear and nonlinear support vector machine classifiers. To find the best combination among the studied factors, we used three approaches: greedy, sequential forward selection (SFS), and exhaustive search. On the basis of our study, we conclude that the factors studied affect the performance of texture methods, so the best combination of these factors should be determined to achieve the best performance with each texture method. SFS can be an appropriate way to approach the factor combination problem because it is less computationally intensive than the other methods.