Hybridization State Detection of DNA-Functionalized Gold Nanoparticles Using Hyperspectral Imaging

Table 1

Dynamic Light Scattering (DLS) and Laser Doppler Velocimetry (LDV) results for unfunctionalized and ssDNA functionalized 13 nm Au NPs.

Sample name	-ave (d⋅nm)	PdI	PdI width (d⋅nm)	ZP (mV)
Particle only
13 nm Au	15.3	0.127	5.46	−9.67
Functionalized particles
A1	39.7	0.211	18.2	−45.9
C1	33.9	0.193	14.9	−47.1
A1-pA	21.1	0.126	7.47	−33.8
C1-pA	27.7	0.231	13.3	−36.1