Clinical Study

Concentrations of H1-Receptor Antagonist in the Human Nasal Mucosa

Table 1

Characters of the participants and results of the concentration of BB in the serum and nasal mucosa.

Sampling time afterConcentrationConcentration
CaseAge (years)Sexoral administrationin the serumin the nasal mucosaAntigen
of BB (h:m)(ng/mL)(ng/g)

Group I153Male1:10155.98111.05Amb, Asp, Candida, Cha, Cry, Dp, HD
225Female1:30132.34108.3Cha, Cry, Dp, HD
329Male1:3567.9847.79Cha, Cry, Dp, HD
468Male1:4098.1476Dp, HD
568Male1:4074.6279.57Candida, Dp, HD
631Male1:4549.3597.3Cha, Cry, Dp, HD
760Male1:5086.8599.2Candida, Cha, Cry, Dp, HD
855Male2:00109.27108.6HD
917Female2:0083.598Amb, Asp, Candida, Dp, HD
1013Male2:10119.41186.1Cry, Dp
Group II1138Female0:5596.22183.67non
1257Male1:0071.3866.7non
1355Female1:20137.21138.2non
1452Male1:20121.58141.5non
1546Male1:3065.04163.88non
1664Female1:30107.48187.01non
1752Female1:40197.55123.85non
1850Male1:4085.1457.86non
1976Male2:00141.6150.57non
2056Male2:0095.47108.7non

Amb: Ambrosia elatior; Asp: Aspergillus; BB: Bepotastine Besilate; Cha: Chamaecyparis obtuse; Cry: Cryptomeria japonica; Dp: Dermatophagoides pteronyssinus; HD: Housedust.