Table of Contents Author Guidelines Submit a Manuscript
International Journal of Otolaryngology
Volume 2009, Article ID 901537, 4 pages
Case Report

Kikuchi-Fujimoto Disease in a 30-Year-Old Caucasian Female

Department of Otorhinolaryngology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA

Received 4 July 2009; Accepted 5 October 2009

Academic Editor: Eugene N. Myers

Copyright © 2009 David J. Archibald et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Kikuchi-Fujimoto disease is a rare, self-limited, histiocytic, necrotizing lymphadenitis first described in Japan in 1972. Necrosis of lymph node tissue is caused by apoptosis and may be virally induced. It commonly presents with cervical lymphadenitis and fever. Despite its low incidence, Kikuchi-Fujimoto disease should be considered in patients with persistent lymphadenopathy. Originally thought to occur only in young Asian women, it is now recognized in other geographic regions. We report a 30-year-old white woman with Kikuchi-Fujimoto disease. We discuss the clinical features, differential diagnosis, radiography, pathology, and outcome.