International Journal of Otolaryngology / 2010 / Article / Tab 2

Clinical Study

Long-Term Histologic Changes in Nasal Mucosa after Total Laryngectomy

Table 2

The comparison of duration of time between laryngectomy and biopsy. Group1, less than 12 months, group 2, 12–36 months, group 3, more than 36 months. *In group 3, three patients have total atrophy; one patient has focal atrophy. In the other groups atrophy is focal. .

Histopathologic changesGroups
Group 1 ( = 4)Group 2 ( = 2)Group 3 ( = 5)

Destruction of goblet cells%50 ( = 2)%100 ( = 2)%100 ( = 5)
Fibrosis in stroma%100 ( = 4)%100 ( = 2)%60 ( = 3)
Destruction of cilia%50 ( = 2)%50 ( = 1)%60 ( = 3)
Destruction of glands%25 ( = 1)%25 ( = 1)%60 ( = 3)
Atrophy%75 ( = 3)%50 ( = 1)%80 ( = 4)*
Neovascularization%50 ( = 2)%40 ( = 2)
Congestion%75 ( = 3)**%50 ( = 1)**
Mixoid degeneration%25 ( = 1)%50 ( = 1)%20 ( = 1)

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