Decreased Risk of Squamous Cell Carcinoma of the Head and Neck in Users of Nonsteroidal Anti-Inflammatory Drugs
Table 1
Characteristics of patients with head and neck cancer and matched controls.
Cases
Controls
()
()
Age, mean (SD)
56
(12)
57
(9.7)
Gender, (%)
Male
61
(86)
61
(86)
Female
10
(14)
10
(14)
Smoking Status, (%)
Ever
55
(73)
55
(73)
Never
16
(27)
16
(27)
Pack-years, (%)
40
14
(26)
15
(27)
41–60
16
(29)
11
(20)
60
21
(38)
24
(44)
Missing
4
(7)
5
(9)
BMI, mean (SD)
Current
26
(5.3)
28
(4.6)
10 years ago
24
(4.0)
24
(4.0)
Alcohol Consumption, (%)
Ever
71
(100)
65
(92)
Never
0
(0)
5
(7)
Missing
0
(0)
1
(1)
Drink-years, (%)
20
18
(25)
16
(24)
21–40
17
(24)
13
(20)
41–60
9
(13)
9
(14)
60
24
(34)
18
(28)
Missing
3
(4)
9
(14)
Education level, (%)
College
38
(54)
17
(24)
College
33
(46)
53
(75)
Missing
0
(0)
1
(1)
Married or living as married, (%)
Yes
42
(60)
54
(76)
No
28
(39)
17
(24)
Missing
1
(1)
0
(0)
NSAID use, (%)
Never
25
(35)
10
(14)
Occasional
27
(38)
24
(34)
Daily
19
(27)
37
(52)
Type of NSAID
*, (%)
Aspirin
14
(75)
29
(78)
Other
3
(16)
5
(14)
Missing
2
(11)
3
(8)
Reason for using NSAID
*, (%)
Headache
2
(11)
0
(0)
Heart disease
9
(47)
24
(65)
Other
7
(37)
11
(30)
Missing
1
(5)
2
(5)
Age of NSAID use initiation, mean (SD)*
56
(9.4)
56
(9.3)
NSAID tablet years
*, (%)
2
6
(32)
7
(19)
2-3
0
(0)
7
(19)
3
8
(42)
13
(35)
Missing
5
(26)
10
(27)
*Among daily users. Missing data: Current BMI unknown for 2 subjects, 10 years ago unknown for 8 subjects, age at NSAID initiation unknown for 5 subjects. SD: Standard Deviation.
