Ototoxicity from Combined Cisplatin and Radiation Treatment: An In Vitro Study

Figure 2

Flow cytometric subG1 phase as determined by PI staining at different time points (3 h, 24 h, 48 h and 72 h) after exposure to 5 Gy of gamma radiation and 0.5 μg/ml of cisplatin (CDDP). Co-treatment with radiation and CDDP resulted in a significant increase in subG1 phase at 72 h. The data shown are the mean + SD of 4 independent experiments.