Novel Therapeutic Strategies for Malignant Salivary Gland Tumors: Lessons Learned from Breast Cancer

Figure 2

Pg suppresses proliferation and invasion of both salivary gland and breast cancer cells. In our recent studies, the inhibitory effect of Pg on the proliferative and invasive activities of the salivary gland and breast tumor cells was demonstrated, suggesting some common mechanisms. In both types of cancers, expression of Id-1 and c-myc was downregulated after Pg treatment, whereas p21 expression level was upregulated.