A Human Head and Neck Squamous Cell Carcinoma Cell Line with Acquired cis-Diamminedichloroplatinum-Resistance Shows Remarkable Upregulation of BRCA1 and Hypersensitivity to Taxane
Figure 2
Western blot analysis of BRCA1 in HNSCC cell lines and their derived CDDP-resistant (CR) cell lines. Marked upregulation of BRCA1 (220 kDa) was observed only in the RPMI2650CR cell line. Beta actin (ACTB) was used as an internal control.